Improving injectable hydrogels for bone repair by incorporating bioactive glass nanoparticles

 

Investigator: Jingjing Wu (Visiting PhD student, Huazhong University of Science and Technology, China)

Jingjing Wu

 

Ulrich-Schalk-Straße 3
91056 Erlangen
Phone: (+49) 1590 8461 089
Email: jingjing.wu@fau.de

 

Supervisor (HUST): Prof. Ying Wan

Supervisor (FAU): Prof. Dr. Ing. Aldo R. Boccaccini

 

Bioactive glasses (BGs) can be doped with specific metallic ions which play additional roles in osteogenesis, angiogenesis and antibacterial applications [1]. When a hydrogel containing BG nanoparticles is used for bone repair, the released ions can promote osteogenesis as such ions interact with osteoblasts while inhibiting bone resorption resulted from osteoclasts. In this project, we intend to prepare composite injectable hydrogels containing a series of ion doped BG particles. The new materials will be characterized in vitro.

[1] A. Hoppe, V. Mouriño, and A.R. Boccaccini, “Therapeutic inorganic ions in bioactive glasses to enhance bone formation and beyond,” Biomater. Sci., 1 [3] 254–256 (2013).